Scientists in China have discovered a new cell biology mechanism of cell "rejuvenation

Induced pluripotent stem cells and functional cell transplantation are considered to be an important means of treating genetic diseases, organ damage, and degenerative diseases such as Parkinson, but the current bottleneck in this field is the lack of understanding of the molecular mechanism. Recently, scientists in China have discovered a new cell biology mechanism, which is expected to promote the application of induced pluripotent stem cell technology to disease treatment more quickly.

The research results of Pei Duanqing and Zheng Hui, researchers from Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, were published online in the international academic journal Nature and Cell Biology on the 26th.

According to reports, the process of inducing pluripotent stem cells can "reverse" normal cells in the human body to the early embryonic development state, thereby regaining the ability to differentiate into most types of cells in the body. The scientist who established the technology obtained the 2012 Nobel Prize in Physiology or Medicine. This cellular-level "rejuvenation" process contains many mysteries of life, but at present, little is known about it.

Scientists in China have long recognized its potential significance and related mechanisms. As early as 2010, Pei Duanqing's team discovered that the cell "reversal" process was driven by the transition of mesenchymal cell status to epithelial cell status. In further research, the team of Pei Duanqing and Zheng Hui found that there was a process of transition from epithelial to mesenchymal cells before the mesenchymal transition to the epithelial cell state, and proved such multiple conversions Conducive to improving the efficiency of reprogramming.

"This finding is consistent with the traditional Chinese concept of Yin-Yang Tai Chi. We further deduce that the mechanism of multiple interconversions between the state of mesenchymal cells and the state of epithelial cells is of high universality and exists in other systems or studies. Said Pei Duanqing.

Scientists say that the discovery that the sequence between mesenchymal cell and epithelial cells will change mutually will further improve the process of reprogramming somatic cells into induced pluripotent stem cells. This new cell biology mechanism is expected to promote theoretical and practical breakthroughs in the research of induced pluripotent stem cells, and open up new ways for stem cells to treat degenerative diseases such as Parkinson's disease.

Little Armchairs And Stools OUTDOOR

Little Armchairs And Stools OUTDOOR,minotti mills chair,minotti mills dining chair,minotti office chair

Foshan Jianermei Furniture Co., Ltd , https://www.minottiitaly.com