MIT invents nano-printing

Researchers at the Massachusetts Institute of Technology invented a new "nano-printing" technology that enables mass production of nanodevices such as DNA microarrays.

With the development of science, from the biomedical to the information technology fields, the volume of the devices used has been continuously reduced and the complexity is increasing. These requirements also inspire scientists to work hard towards nanometer printing technology with high resolution and high throughput. Direction study. In response to this, a team led by Francesco Stellacci, a professor of materials science and engineering at MIT, developed a new technology with high information capacity and print resolution. They use one of nature's most effective printing technologies: DNA/RNA messaging technology.

In this new technique called Supramolecular Nano-Stamping (SuNS), single-stranded DNA replicates another DNA strand and then self-assembles to form a complete double-stranded DNA pattern. The copied DNA strand is exactly the same as the parent strand and can therefore be used as a template to continue replication. This will not only increase the output of the printing but also reproduce a very complex nanoscale pattern.

DNA microarrays are nanodevices used to diagnose and understand genetic diseases (such as Alzheimer's), viral diseases (such as AIDS) and certain cancers. It is usually made of silicon or glass chips with nearly 500,000 tiny dots printed on it. Each point consists of multiple DNA molecules with a known sequence, which means that each chip contains a person's genetic code. Using DNA microarrays, scientists can discover and analyze the genetic code of a person's DNA or messenger RNA, so that he can diagnose liver cancer early or predict the chances of a couple having a child with a genetic disease.


Source: Zhongchuang

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